Roche
South San Francisco, CA, USA
The Position The department of Structural Biology at Genentech has an exciting opportunity for a Senior Scientist with a strong background in protein biochemistry and structural biology. This scientist will be responsible for the production of high-quality protein reagents to support small molecule drug discovery, antibody discovery, lead finding efforts such as high-throughput screening, DNA-encoded library technologies, and structure-based drug design. The scientist will also be responsible to improve upon current state-of-the-art methods to accelerate research processes. A proven track-record in optimizing the expression and purification of challenging proteins for functional and structural studies, including through protein engineering, is essential. Highly desirable hands-on experiences include: (a) Different protein classes and (b) Biochemical / structural characterization of multiprotein complexes obtained through in-vitro assembly of over-expressed and purified...