At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com
Job Function: Career Programs
Job Sub Function: Non-LDP Intern/Co-Op
Job Category:Career Program
All Job Posting Locations:Spring House, Pennsylvania, United States of America
Job Description:Internship in Synthetic Organic Chemistry, Johnson & Johnson Spring House (Graduate Student)Job Description: The Discovery Process Research (DPR) group of Johnson & Johnson Innovative Medicine is seeking an outstanding and motivated graduate student for a summer internship, to be based in Spring House, PA. This internship is designed for
advanced PhD candidates (students who have completed at least their third year of graduate research) with prior training in
synthetic organic chemistry and a strong interest in
reaction discovery and optimization. This role will provide the intern with exposure to the Johnson and Johnson Innovative Medicine research engine at the intersection between Discovery and Process chemistry. Interns will gain real-life training in the skills and tools relevant to employment within the broader area of drug discovery. Beyond gaining industrial experience and networking, the intern will contribute to the design and development of
novel, robust, and scalable chemical transformations at the interface of small-molecule and peptide chemistry with an opportunity to present and publish their work.
The synthetic organic chemistry intern will:
- Design and execute exploratory experiments focused on reaction discovery and optimization
- Develop and evaluate synthetic routes for small molecules and peptide intermediates
- In the peptide space, the intern will perform solid-phase peptide synthesis (SPPS) and explore on-resin and late-stage peptide functionalization, including side-chain modification, ligation, or conjugation strategies
- In the small molecule space, the intern will leverage high throughput experimentation techniques and catalysis to enable address key synthetic challenges
• Synthesize, purify, and characterize relevant organic compounds
- Analyze products and intermediates using NMR, LC-MS, HPLC, and related techniques
- Maintain thorough and compliant electronic laboratory notebook (ELN) documentation
- Prepare technical reports and present findings to cross-functional project teams
- Be exposed to various other functions within the drug discovery teams at Johnson & Johnson
- Participate in campus-wide activities across the Spring House summer intern community
- Be based in Spring House, PA (suburban Philadelphia area)
Internship Details- Duration: 10-12 weeks
- Location: Spring House, PA [On-site]
- Compensation: Competitive, paid internship
- Start date: Flexible within program window
Required Qualifications- Current enrollment in an accredited college/university pursuing a Ph.D. degree in a field related to organic chemistry
- Completion of at least three years of graduate research by the start of the internship with a strong foundation in synthetic organic chemistry
- Familiarity with standard analytical techniques (NMR, MS, HPLC) and synthetic workflows (work-ups, isolations, recrystallization, column chromatography)
- Availability to work full-time during the internship period
- Strong organizational skills, rigor, and proven track record to balance multiple tasks
- Capacity to work independently as well as on a team
- Legal authorization to work in the United States and not require sponsorship for employment visa status (e.g. H1-B status) now or in the future
- Proficiency with Microsoft Office, Word, Excel, and Power Point, and have strong oral and written communication skills
- A minimum G.P.A. of 3.2 is strongly preferred
- Preferred Qualifications: Experience with any or all of the following synthetic paradigms: Solid Phase Peptide Synthesis, Photochemistry, Radical Chemistry, Cross-Coupling, Molecular Editing, Total Synthesis
Equal Opportunity Statement: Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
About the Discovery Process Research Group: Discovery Process Research at Johnson & Johnson sits at the critical interface between discovery and development. Our teams focus on enabling the rapid and reliable translation of novel chemical ideas into robust, scalable synthetic processes that support the advancement of small-molecule and emerging modality programs, including peptides, antibody drug conjugates, and oligonucleotides. Through reaction discovery, route scouting, and early process design, we partner closely with medicinal chemistry, analytical, and development organizations to shape high-quality synthetic strategies from the earliest stages of a program. By combining deep expertise in synthetic organic and peptide chemistry with a strong emphasis on safety, sustainability, and manufacturability, Discovery Process Research plays a key role in de-risking development, accelerating timelines, and delivering innovative medicines to patients worldwide.
About Johnson and Johnson and Our Mission: At Johnson & Johnson, we believe good health is the foundation of vibrant lives, thriving communities, and forward progress. For more than 135 years, we have been committed to advancing health through science, innovation, and a deep responsibility to patients around the world. Our organization focuses on developing transformational medicines across areas of significant unmet need, including oncology, immunology, neuroscience, infectious diseases, and cardiovascular and metabolic disorders. Our teams bring together world-class scientists, cutting-edge technologies, and a strong culture of collaboration to help build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Guided by Our Credo, we are committed to conducting science with integrity, advancing sustainability, and fostering an inclusive environment where diverse perspectives drive innovation. Learn more at www.jnj.com.
Permanently authorized to work in the U.S., must not require sponsorship of an employment visa (e.g., H-1B or green card) at the time of application or in the future. Students currently on CPT, OPT, or STEM OPT usually requires future sponsorship for long term employment and do not meet the requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via
https://www.jnj.com/contact-us/careers . internal employees contact AskGS to be directed to your accommodation resource.
Required Skills: Preferred Skills:
